Dosing regimen of meropenem for adults with severe burns: a population pharmacokinetic study with Monte Carlo simulations | Zendy

Amelia RamonLopez | Zendy; Janet M. Allen | Zendy; Alison H. Thomson | Zendy; Baljit Dheansa | Zendy; S. Elizabeth James | Zendy; G.W. Hanlon | Zendy; Brock Stewart | Zendy; Graham Davies | Zendy

Open Access

Dosing regimen of meropenem for adults with severe burns: a population pharmacokinetic study with Monte Carlo simulations

Author(s) -

Amelia RamonLopez,

Janet M. Allen,

Alison H. Thomson,

Baljit Dheansa,

S. Elizabeth James,

G.W. Hanlon,

Brock Stewart,

Graham Davies

Publication year - 2014

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dku429

Subject(s) - meropenem , pharmacokinetics , nonmem , medicine , dosing , population , pharmacology , regimen , antibacterial agent , antibiotics , microbiology and biotechnology , biology , environmental health , antibiotic resistance

To develop a population model to describe the pharmacokinetics (PK) of intravenous meropenem in adult patients with severe burns and investigate potential relationships between dosage regimens and antimicrobial efficacy.

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