Are interstitial fluid concentrations of meropenem equivalent to plasma concentrations in critically ill patients receiving continuous renal replacement therapy? | Zendy

Julie Varghese | Zendy; Paul Jarrett | Zendy; Steven C. Wallis | Zendy; Robert Boots | Zendy; Carl M. J. Kirkpatrick | Zendy; Jeffrey Lipman | Zendy; Jason A. Roberts | Zendy

Open Access

Are interstitial fluid concentrations of meropenem equivalent to plasma concentrations in critically ill patients receiving continuous renal replacement therapy?

Author(s) -

Julie Varghese,

Paul Jarrett,

Steven C. Wallis,

Robert Boots,

Carl M. J. Kirkpatrick,

Jeffrey Lipman,

Jason A. Roberts

Publication year - 2014

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dku413

Subject(s) - meropenem , pharmacokinetics , volume of distribution , trough concentration , microdialysis , medicine , interstitial fluid , pharmacodynamics , urology , pharmacology , chemistry , anesthesia , antibiotics , biochemistry , antibiotic resistance , central nervous system

To describe the interstitial fluid (ISF) and plasma pharmacokinetics of meropenem in patients on continuous venovenous haemodiafiltration (CVVHDF).

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