Redox-active compounds with a history of human use: antistaphylococcal action and potential for repurposing as topical antibiofilm agents | Zendy

Nicola Ooi | Zendy; E.A. Eady | Zendy; Jonathan H. Cove | Zendy; Alex J. O’Neill | Zendy

Open Access

Redox-active compounds with a history of human use: antistaphylococcal action and potential for repurposing as topical antibiofilm agents

Author(s) -

Nicola Ooi,

E.A. Eady,

Jonathan H. Cove,

Alex J. O’Neill

Publication year - 2014

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dku409

Subject(s) - repurposing , biofilm , staphylococcus aureus , mode of action , redox , antibacterial agent , drug repositioning , staphylococcal infections , medicine , chemistry , pharmacology , microbiology and biotechnology , antibiotics , drug , biology , bacteria , biochemistry , genetics , ecology , organic chemistry

To investigate the antistaphylococcal/antibiofilm activity and mode of action (MOA) of a panel of redox-active (RA) compounds with a history of human use and to provide a preliminary preclinical assessment of their potential for topical treatment of staphylococcal infections, including those involving a biofilm component.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research