Azole, polyene and echinocandin MIC distributions for wild-type, TR34/L98H and TR46/Y121F/T289A Aspergillus fumigatus isolates in the Netherlands | Zendy

Jakko van Ingen | Zendy; Henrich A. van der Lee | Zendy; T. A. J. Rijs | Zendy; Jan Zoll | Zendy; Tjalling Leenstra | Zendy; Willem J. G. Melchers | Zendy; Paul E. Verweij | Zendy

Open Access

Azole, polyene and echinocandin MIC distributions for wild-type, TR34/L98H and TR46/Y121F/T289A Aspergillus fumigatus isolates in the Netherlands

Author(s) -

Jakko van Ingen,

Henrich A. van der Lee,

T. A. J. Rijs,

Jan Zoll,

Tjalling Leenstra,

Willem J. G. Melchers,

Paul E. Verweij

Publication year - 2014

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dku364

Subject(s) - posaconazole , aspergillus fumigatus , itraconazole , microbiology and biotechnology , voriconazole , azole , biology , echinocandin , anidulafungin , antifungal , fluconazole , micafungin

To determine the MIC distributions of itraconazole, voriconazole and posaconazole and non-azole drugs for wild-type cyp51A, as well as TR(34)/L98H and TR(46)/Y121F/T289A cyp51A mutants of Aspergillus fumigatus.

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