Randomized non-inferiority trial to compare trimethoprim/sulfamethoxazole plus rifampicin versus linezolid for the treatment of MRSA infection
Author(s) -
Stephan Harbarth,
Elodie von Dach,
Léonardo Pagani,
Marina Macedo-Viñas,
Benedikt Huttner,
Flaminia Olearo,
Stéphane Emonet,
İlker Uçkay
Publication year - 2014
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dku352
Subject(s) - linezolid , medicine , trimethoprim , rifampicin , sulfamethoxazole , antibacterial agent , antibiotics , methicillin resistant staphylococcus aureus , randomized controlled trial , staphylococcus aureus , microbiology and biotechnology , tuberculosis , vancomycin , biology , pathology , bacteria , genetics
The therapeutic arsenal for MRSA infections is limited. The aim of this study was to assess the non-inferiority of a combination of trimethoprim/sulfamethoxazole plus rifampicin versus linezolid alone for the treatment of MRSA infection.
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