In vitro activities of the novel bicyclolides modithromycin (EDP-420, EP-013420, S-013420) and EDP-322 against MDR clinical Neisseria gonorrhoeae isolates and international reference strains
Author(s) -
Susanne Jacobsson,
Daniel Golparian,
Ly Phan,
Makoto Ohnishi,
Hans Fredlund,
Yat Sun Or,
Magnus Unemo
Publication year - 2014
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dku344
Subject(s) - neisseria gonorrhoeae , microbiology and biotechnology , antimicrobial , in vitro , neisseriaceae , biology , neisseria , antibiotics , virology , bacteria , genetics
New antimicrobials are essential to prevent gonorrhoea becoming an untreatable infection. Herein, the in vitro activities of the novel bicyclolides modithromycin (EDP-420, EP-013420, S-013420) and EDP-322 against Neisseria gonorrhoeae strains were investigated and compared with antimicrobials currently or previously recommended for treatment of gonorrhoea.
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