Meropenem/colistin synergy testing for multidrug-resistant Acinetobacter baumannii strains by a two-dimensional gradient technique applicable in routine microbiology | Zendy

Alex van Belkum | Zendy; Diane Halimi | Zendy; Eve J. Bonetti | Zendy; Gesuèle Renzi | Zendy; Abdessalam Cherkaoui | Zendy; Véronique Sauvonnet | Zendy; Rolland Martelin | Zendy; G. Durand | Zendy; Sonia Chatellier | Zendy; Gilles Zambardi | Zendy; A. Engelhardt | Zendy; Åsa Karlsson | Zendy; Jacques Schrenzel | Zendy

Open Access

Meropenem/colistin synergy testing for multidrug-resistant Acinetobacter baumannii strains by a two-dimensional gradient technique applicable in routine microbiology

Author(s) -

Alex van Belkum,

Diane Halimi,

Eve J. Bonetti,

Gesuèle Renzi,

Abdessalam Cherkaoui,

Véronique Sauvonnet,

Rolland Martelin,

G. Durand,

Sonia Chatellier,

Gilles Zambardi,

A. Engelhardt,

Åsa Karlsson,

Jacques Schrenzel

Publication year - 2014

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dku342

Subject(s) - acinetobacter baumannii , meropenem , colistin , microbiology and biotechnology , antimicrobial , biology , antibiotics , medicine , antibiotic resistance , bacteria , pseudomonas aeruginosa , genetics

Precise assessment of potential therapeutic synergy, antagonism or indifference between antimicrobial agents currently depends on time-consuming and hard-to-standardize in vitro chequerboard titration methods. We here present a method based on a novel two-dimensional antibiotic gradient technique named Xact™.

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