Bacteraemia incidence, causative organisms and resistance patterns, antibiotic strategies and outcomes in a single university hospital ICU: continuing improvement between 2000 and 2013
Author(s) -
Vincenzo De Santis,
Mihaela Gresoiu,
Alberto Corona,
A.P.R. Wilson,
Mervyn Singer
Publication year - 2014
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dku338
Subject(s) - medicine , incidence (geometry) , antibiotic resistance , antibiotics , bacteremia , cohort , prospective cohort study , intensive care medicine , antimicrobial , fluconazole , microbiology and biotechnology , antifungal , physics , dermatology , optics , biology
The optimal duration of antibiotic treatment in patients with bloodstream infections remains contentious, with concerns regarding both undertreatment and the encouragement of antibiotic resistance. In our ICU we traditionally use short-course antibiotic monotherapy as the mainstay of treatment. We sought to document the impact of this strategy on pathogen type, resistance patterns and patient outcomes. A comparison was made against data collected during a similar exercise in 2000.
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