Interplay between plasmid-mediated and chromosomal-mediated fluoroquinolone resistance and bacterial fitness in Escherichia coli | Zendy

Jesús Machuca | Zendy; A. Briales | Zendy; G. Labrador | Zendy; Paula Díaz-De-Alba | Zendy; Rafael López-Rojas | Zendy; Fernando Docobo-Pérez | Zendy; Luis MartínezMartínez | Zendy; Jesús RodríguezBaño | Zendy; M. E. Pachon | Zendy; Álvaro Pascual | Zendy; José Manuel Rodríguez-Martínez | Zendy

Open Access

Interplay between plasmid-mediated and chromosomal-mediated fluoroquinolone resistance and bacterial fitness in Escherichia coli

Author(s) -

Jesús Machuca,

A. Briales,

G. Labrador,

Paula Díaz-De-Alba,

Rafael López-Rojas,

Fernando Docobo-Pérez,

Luis MartínezMartínez,

Jesús RodríguezBaño,

M. E. Pachon,

Álvaro Pascual,

José Manuel Rodríguez-Martínez

Publication year - 2014

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dku308

Subject(s) - plasmid , escherichia coli , biology , genetics , gene , microbiology and biotechnology , enterobacteriaceae , bacterial genetics , antibiotic resistance , bacteria

The aim of this study was to analyse the interplay among plasmid-mediated qnr genes, alone or in combination with multiple chromosomal-mediated fluoroquinolone (FQ) resistance determinants, susceptibility to FQs and bacterial fitness in an isogenic Escherichia coli collection.

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