Antibiotic prophylaxis for transrectal prostate biopsy--a new strategy | Zendy

Valeria Antsupova | Zendy; Nis Nørgaard | Zendy; Rasmus Bisbjerg | Zendy; Jette Nygaard Jensen | Zendy; Jonas Bredtoft Boel | Zendy; J. O. Jarløv | Zendy; Magnus Arpi | Zendy

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Antibiotic prophylaxis for transrectal prostate biopsy--a new strategy

Author(s) -

Valeria Antsupova,

Nis Nørgaard,

Rasmus Bisbjerg,

Jette Nygaard Jensen,

Jonas Bredtoft Boel,

J. O. Jarløv,

Magnus Arpi

Publication year - 2014

Publication title -

journal of antimicrobial chemotherapy

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dku293

Subject(s) - medicine , antibiotic prophylaxis , prostate , antibiotics , prostate biopsy , intensive care medicine , microbiology and biotechnology , biology , cancer

Fluoroquinolones are extensively used as prophylaxis for transrectal ultrasound-guided biopsy of the prostate (TRUBP). Emerging fluoroquinolone resistance and selection of multiresistant organisms warrant new prophylactic strategies. Pivmecillinam and amoxicillin/clavulanic acid have mutual synergistic activity and the combination of these agents has a broad coverage of the majority of microorganisms causing infectious complications after TRUBP and may be a valuable future prophylactic regimen.

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