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Virological efficacy of abacavir: systematic review and meta-analysis
Author(s) -
Mario Cruciani,
Carlo Mengoli,
Marina Malena,
Giovanni Serpelloni,
Saverio Giuseppe Parisi,
Graeme Moyle,
Oliviero Bosco
Publication year - 2014
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dku279
Subject(s) - abacavir , emtricitabine , lamivudine , medicine , meta analysis , tenofovir , randomized controlled trial , human immunodeficiency virus (hiv) , virology , chronic hepatitis , virus
The efficacy of abacavir/lamivudine has been reported to be inferior to tenofovir/emtricitabine. Several randomized clinical trials (RCTs) investigated the effectiveness and safety of abacavir/lamivudine and tenofovir/emtricitabine combined antiretroviral treatment (cART) and we have reviewed the available evidence.

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