Invasive aspergillosis caused by Aspergillus terreus: an emerging opportunistic infection with poor outcome independent of azole therapy
Author(s) -
Ray Hachem,
Marisa Zenaide Ribeiro Gomes,
G. Helou,
Aline El Zakhem,
Cynthia Kassis,
Ester Silveira Ramos,
Ying Jiang,
AnneMarie Chaftari,
Issam Raad
Publication year - 2014
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dku241
Subject(s) - aspergillus terreus , aspergillosis , aspergillus , azole , malignancy , medicine , mycosis , biology , population , microbiology and biotechnology , surgery , immunology , antifungal , environmental health
Invasive aspergillosis (IA) caused by Aspergillus terreus is a significant cause of morbidity and mortality in patients with haematological malignancy (HM). Very few data are available in this patient population to differentiate IA patients with A. terreus from those with non-terreus species of Aspergillus to compare outcomes. We retrospectively investigated 513 HM patients who were treated for either definite or probable IA between June 1993 and August 2012 in a cancer centre.
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