Deficiency of the ferrous iron transporter FeoAB is linked with metronidazole resistance in Bacteroides fragilis | Zendy

Yaligara Veeranagouda | Zendy; Fasahath Husain | Zendy; Renata F. Boente | Zendy; Jane Moore | Zendy; C. Jeffrey Smith | Zendy; Edson R. Rocha | Zendy; Sheila Patrick | Zendy; Hannah M. Wexler | Zendy

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Deficiency of the ferrous iron transporter FeoAB is linked with metronidazole resistance in Bacteroides fragilis

Author(s) -

Yaligara Veeranagouda,

Fasahath Husain,

Renata F. Boente,

Jane Moore,

C. Jeffrey Smith,

Edson R. Rocha,

Sheila Patrick,

Hannah M. Wexler

Publication year - 2014

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dku219

Subject(s) - bacteroides fragilis , metronidazole , microbiology and biotechnology , antimicrobial , ferrous , bacteroides , antibiotic resistance , medicine , antibiotics , biology , chemistry , bacteria , organic chemistry , genetics

Metronidazole is the most commonly used antimicrobial for Bacteroides fragilis infections and is recommended for prophylaxis of colorectal surgery. Metronidazole resistance is increasing and the mechanisms of resistance are not clear.

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