Clinical significance of 2 h plasma concentrations of first-line anti-tuberculosis drugs: a prospective observational study | Zendy

Julie B. Prahl | Zendy; Işık Somuncu Johansen | Zendy; Alan S. Cohen | Zendy; Niels FrimodtMøller | Zendy; Åse Bengård Andersen | Zendy

Open Access

Clinical significance of 2 h plasma concentrations of first-line anti-tuberculosis drugs: a prospective observational study

Author(s) -

Julie B. Prahl,

Işık Somuncu Johansen,

Alan S. Cohen,

Niels FrimodtMøller,

Åse Bengård Andersen

Publication year - 2014

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dku210

Subject(s) - ethambutol , pyrazinamide , rifampicin , tuberculosis , isoniazid , medicine , observational study , antibacterial agent , prospective cohort study , cohort study , pharmacology , antibiotics , microbiology and biotechnology , pathology , biology

To study 2 h plasma concentrations of the first-line tuberculosis drugs isoniazid, rifampicin, ethambutol and pyrazinamide in a cohort of patients with tuberculosis in Denmark and to determine the relationship between the concentrations and the clinical outcome.

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