Open AccessPopulation pharmacokinetics and dosing simulations of cefuroxime in critically ill patients: non-standard dosing approaches are required to achieve therapeutic exposures
Author(s) -
Mieke Carlier,
Michaël Noë,
Jason A. Roberts,
Veronique Stove,
Alain Verstraete,
Jeffrey Lipman,
Jan J. De Waele
Publication year - 2014
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dku195
Subject(s) - pharmacokinetics , dosing , pharmacodynamics , population , medicine , cefuroxime , pharmacology , nonmem , bolus (digestion) , antibiotics , chemistry , biochemistry , environmental health
To investigate the population pharmacokinetics of cefuroxime in critically ill patients.
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