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Antimicrobial activity of ceftolozane/tazobactam tested against Pseudomonas aeruginosa and Enterobacteriaceae with various resistance patterns isolated in European hospitals (2011–12)
Author(s) -
Hélio S. Sader,
David J. Farrell,
Mariana Castanheira,
Robert K. Flamm,
Ronald N. Jones
Publication year - 2014
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dku184
Subject(s) - broth microdilution , meropenem , microbiology and biotechnology , ceftazidime , pseudomonas aeruginosa , tigecycline , colistin , tazobactam , ceftazidime/avibactam , cephalosporin , biology , antimicrobial , minimum inhibitory concentration , antibiotics , medicine , imipenem , antibiotic resistance , bacteria , genetics
To evaluate the in vitro activity of ceftolozane/tazobactam and comparator agents tested against contemporary Gram-negative bacteria. Ceftolozane/tazobactam is an antipseudomonal cephalosporin combined with a well-established β-lactamase inhibitor.

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