Tenofovir diphosphate concentrations and prophylactic effect in a macaque model of rectal simian HIV transmission | Zendy

Peter L. Anderson | Zendy; David V. Glidden | Zendy; Lane R. Bushman | Zendy; Walid Heneine | Zendy; J. Gerardo Garcı́a-Lerma | Zendy

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Tenofovir diphosphate concentrations and prophylactic effect in a macaque model of rectal simian HIV transmission

Author(s) -

Peter L. Anderson,

David V. Glidden,

Lane R. Bushman,

Walid Heneine,

J. Gerardo Garcı́a-Lerma

Publication year - 2014

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dku162

Subject(s) - tenofovir , simian , simian immunodeficiency virus , macaque , virology , human immunodeficiency virus (hiv) , transmission (telecommunications) , medicine , rectum , virus , biology , computer science , paleontology , telecommunications

This study evaluated the relationship between intracellular tenofovir diphosphate concentrations in peripheral blood mononuclear cells and prophylactic efficacy in a macaque model for HIV pre-exposure prophylaxis (PrEP).

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