Open AccessHigh level of HIV-1 resistance in patients failing long-term first-line antiretroviral therapy in Mali
Author(s) -
Djeneba Bocar Fofana,
Cathia Soulié,
Aliou Baldé,
Sidonie Lambert-Niclot,
Mariam Sylla,
Zaïna Ait-Arkoub,
Fodié Diallo,
Boubou Sangare,
Mamadou Cissé,
I. Maïga,
Slim Fourati,
Ousmane Koïta,
Vincent Cálvez,
AnneGeneviève Marcelin,
Almoustapha Issiaka Maïga
Publication year - 2014
Publication title -
the journal of antimicrobial chemotherapy/journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dku153
Subject(s) - rilpivirine , etravirine , medicine , reverse transcriptase inhibitor , viral load , resistance mutation , virology , drug resistance , lamivudine , reverse transcriptase , regimen , nucleoside reverse transcriptase inhibitor , genotype , dolutegravir , coinfection , efavirenz , gastroenterology , human immunodeficiency virus (hiv) , antiretroviral therapy , biology , virus , polymerase chain reaction , hepatitis b virus , microbiology and biotechnology , biochemistry , gene
In resource-limited settings, few data are available on virological failure after long-term first-line antiretroviral therapy. This study characterized the genotypic resistance patterns at the time of failure after at least 36 months of a first-line regimen in Mali, West Africa.