Open AccessHumanized tissue pharmacodynamics of cefazolin against commonly isolated pathogens in skin and skin structure infections
Author(s) -
Jami G. Jain,
Seth T. Housman,
David P. Nicolau
Publication year - 2014
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dku152
Subject(s) - cefazolin , pharmacodynamics , skin infection , medicine , microbiology and biotechnology , pathogenic organism , antibiotics , biology , pharmacology , pharmacokinetics , staphylococcus aureus , bacteria , genetics
The objective of this study was to assess the efficacy of humanized cefazolin tissue concentrations against methicillin-susceptible Staphylococcus aureus (MSSA) and Enterobacteriaceae in an in vitro pharmacodynamic model.
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