Amphotericin B transfer to CSF following intravenous administration of liposomal amphotericin B
Author(s) -
Volker Strenger,
Andreas Meinitzer,
Josef Donnerer,
Nora Hofer,
Hans Jürgen Dornbusch,
U. Wanz,
Markus G. Seidel,
Daniela Sperl,
Herwig Lackner,
Wolfgang Schwinger,
Petra Sovinz,
Martin Benesch,
C. Urban
Publication year - 2014
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dku148
Subject(s) - amphotericin b , medicine , pharmacokinetics , intravenous infusions , cerebrospinal fluid , route of administration , intrathecal , pharmacology , antibiotics , anesthesia , chemotherapy , gastroenterology , biology , antifungal , microbiology and biotechnology , dermatology
Although amphotericin B (AmB) and its lipid formulations are used for the treatment of fungal infections of the CNS, the kinetics of AmB in the CSF after intravenous administration of liposomal amphotericin B (LAmB) are not well characterized.
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