Comparative replication capacity of raltegravir-resistant strains and antiviral activity of the new-generation integrase inhibitor dolutegravir in human primary macrophages and lymphocytes | Zendy

Michela Pollicita | Zendy; Matteo Surdo | Zendy; F. Di Santo | Zendy; María Francesca Cortese | Zendy; Lavinia Fabeni | Zendy; Valentina Fedele | Zendy; Isabelle Malet | Zendy; AnneGeneviève Marcelin | Zendy; Vincent Cálvez | Zendy; Francesca CeccheriniSilberstein | Zendy; Carlo Federico Perno | Zendy; Valentina Svicher | Zendy

Open Access

Comparative replication capacity of raltegravir-resistant strains and antiviral activity of the new-generation integrase inhibitor dolutegravir in human primary macrophages and lymphocytes

Author(s) -

Michela Pollicita,

Matteo Surdo,

F. Di Santo,

María Francesca Cortese,

Lavinia Fabeni,

Valentina Fedele,

Isabelle Malet,

AnneGeneviève Marcelin,

Vincent Cálvez,

Francesca CeccheriniSilberstein,

Carlo Federico Perno,

Valentina Svicher

Publication year - 2014

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dku144

Subject(s) - dolutegravir , raltegravir , integrase inhibitor , virology , integrase , viral replication , biology , medicine , microbiology and biotechnology , virus , human immunodeficiency virus (hiv) , viral load , antiretroviral therapy

To evaluate the replication capacity and phenotypic susceptibility to dolutegravir and raltegravir of wild-type and raltegravir-resistant HIV-1 strains in several cellular systems.

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