ABCC2*1C and plasma tenofovir concentration are correlated to decreased glomerular filtration rate in patients receiving a tenofovir-containing antiretroviral regimen
Author(s) -
Weerawat Manosuthi,
Chonlaphat Sukasem,
Supeda Thongyen,
Samruay Nilkamhang,
Somnuek Sungkanuparph
Publication year - 2014
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dku129
Subject(s) - renal function , efavirenz , tenofovir , medicine , emtricitabine , gastroenterology , creatinine , regimen , lamivudine , viral load , human immunodeficiency virus (hiv) , antiretroviral therapy , virology , virus , hepatitis b virus
To study the correlations of genetic variants of tenofovir tubular transporters, plasma tenofovir concentrations and clinical factors with decreased glomerular filtration rate in HIV-infected patients who received tenofovir.
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