Treatment failure with 2 g of azithromycin (extended-release formulation) in gonorrhoea in Japan caused by the international multidrug-resistant ST1407 strain of Neisseria gonorrhoeae | Zendy

Tomoko MoritaIshihara | Zendy; Magnus Unemo | Zendy; Keiichi Furubayashi | Zendy; Takuya Kawahata | Zendy; Ken Shimuta | Zendy; Shuichi Nakayama | Zendy; Makoto Ohnishi | Zendy

Open Access

Treatment failure with 2 g of azithromycin (extended-release formulation) in gonorrhoea in Japan caused by the international multidrug-resistant ST1407 strain of Neisseria gonorrhoeae

Author(s) -

Tomoko MoritaIshihara,

Magnus Unemo,

Keiichi Furubayashi,

Takuya Kawahata,

Ken Shimuta,

Shuichi Nakayama,

Makoto Ohnishi

Publication year - 2014

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dku118

Subject(s) - neisseria gonorrhoeae , mtrr , multilocus sequence typing , microbiology and biotechnology , biology , azithromycin , etest , spectinomycin , antibiotic resistance , cefpodoxime , multiple loci vntr analysis , virology , cephalosporin , genetics , antimicrobial , genotype , antibiotics , variable number tandem repeat , gene , methylenetetrahydrofolate reductase

Antimicrobial resistance in Neisseria gonorrhoeae is a major public health concern globally. We report the first verified treatment failure of gonorrhoea with 2 g of azithromycin (extended-release formulation) in Japan and characteristics of the corresponding N. gonorrhoeae isolates.

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