Glycopeptide use is associated with increased mortality in Enterococcus faecalis bacteraemia
Author(s) -
H. Foo,
Michel Sebba Chater,
Michael Maley,
Sebastiaan J. van Hal
Publication year - 2014
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dku107
Subject(s) - medicine , glycopeptide , antimicrobial , enterococcus faecalis , enterococcus , bacteremia , retrospective cohort study , antibiotics , surgery , microbiology and biotechnology , staphylococcus aureus , biology , bacteria , genetics
Enterococci are an important cause of nosocomial and community-acquired infections, with bacteraemia being one of the most common presentations. Although inappropriate antimicrobial therapy has been associated with poorer outcomes in Enterococcus faecalis (EF) bacteraemia, the impact of antimicrobial choice, namely β-lactam versus glycopeptide therapy, has not been well described. We sought to determine whether choice of antibiotic affects patient outcomes in EF bacteraemia.
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