Detection of carbapenemase activity directly from blood culture vials using MALDI-TOF MS: a quick answer for the right decision | Zendy

Cecília G Carvalhaes | Zendy; Rodrigo Cayô | Zendy; Marina Francisco Visconde | Zendy; Talita Barone | Zendy; Eliete A. M. Frigatto | Zendy; Débora Noma Okamoto | Zendy; Diego M. Assis | Zendy; Luiz Juliano | Zendy; Antonia M.O. Machado | Zendy; Ana Cristina Gales | Zendy

Open Access

Detection of carbapenemase activity directly from blood culture vials using MALDI-TOF MS: a quick answer for the right decision

Author(s) -

Cecília G Carvalhaes,

Rodrigo Cayô,

Marina Francisco Visconde,

Talita Barone,

Eliete A. M. Frigatto,

Débora Noma Okamoto,

Diego M. Assis,

Luiz Juliano,

Antonia M.O. Machado,

Ana Cristina Gales

Publication year - 2014

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dku094

Subject(s) - acinetobacter baumannii , vial , blood culture , microbiology and biotechnology , matrix assisted laser desorption/ionization , mass spectrometry , clinical microbiology , biology , chromatography , bacteria , chemistry , pseudomonas aeruginosa , antibiotics , genetics , organic chemistry , adsorption , desorption

Recently, matrix-assisted laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF MS) was successfully applied for the detection of carbapenemase activity directly from Gram-negative colonies. Based on this principle, we evaluated the performance of MALDI-TOF MS for rapid detection of carbapenemase activity directly from positive blood culture vials.

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