Evaluation of the pharmacodynamic profile of commonly used intravenous vancomycin dosing schemes in patients on automated peritoneal dialysis | Zendy

Katie E. Cardone | Zendy; Wen Zhen Chen | Zendy; Darren W. Grabe | Zendy; Amber Batzold | Zendy; Harold J. Manley | Zendy; Thomas P. Lodise | Zendy

Open Access

Evaluation of the pharmacodynamic profile of commonly used intravenous vancomycin dosing schemes in patients on automated peritoneal dialysis

Author(s) -

Katie E. Cardone,

Wen Zhen Chen,

Darren W. Grabe,

Amber Batzold,

Harold J. Manley,

Thomas P. Lodise

Publication year - 2014

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dku081

Subject(s) - dosing , vancomycin , medicine , peritoneal dialysis , pharmacokinetics , pharmacodynamics , regimen , peritonitis , pharmacology , staphylococcus aureus , biology , bacteria , genetics

The intent of this study was to evaluate the appropriateness of commonly used intravenous (iv) vancomycin dosing schemes in patients on automated peritoneal dialysis (APD) using population pharmacokinetic (PK) modelling and Monte Carlo simulation.

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