Novel oral anti-influenza drug candidate AV5080
Author(s) -
Alexandre V. Ivachtchenko,
Yan A. Ivanenkov,
Oleg D. Mitkin,
Pavel Yamanushkin,
V. Bichko,
Natalia A. Shevkun,
Ruben N. Karapetian,
Irina A. Leneva,
О. В. Борисова,
Mark S. Veselov
Publication year - 2014
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dku074
Subject(s) - oseltamivir , neuraminidase , neuraminidase inhibitor , potency , drug candidate , virology , drug , influenza a virus , human influenza , virus , drug resistance , medicine , microbiology and biotechnology , pharmacology , biology , covid-19 , in vitro , infectious disease (medical specialty) , biochemistry , disease
Development of a novel drug candidate with improved potency against influenza virus neuraminidase compared with currently available therapeutics, and high activity against oseltamivir-resistant viruses.
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