An unusual class of anthracyclines potentiate Gram-positive antibiotics in intrinsically resistant Gram-negative bacteria | Zendy

Georgina Cox | Zendy; Kalinka Koteva | Zendy; Gerard D. Wright | Zendy

Open Access

An unusual class of anthracyclines potentiate Gram-positive antibiotics in intrinsically resistant Gram-negative bacteria

Author(s) -

Georgina Cox,

Kalinka Koteva,

Gerard D. Wright

Publication year - 2014

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dku057

Subject(s) - gram , gram negative bacteria , antibiotics , microbiology and biotechnology , gram positive bacteria , bacteria , biology , gram negative bacterial infections , escherichia coli , genetics , gene

An orthogonal approach taken towards novel antibacterial drug discovery involves the identification of small molecules that potentiate or enhance the activity of existing antibacterial agents. This study aimed to identify natural-product rifampicin adjuvants in the intrinsically resistant organism Escherichia coli.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research