Effect of antibiotic stewardship programmes on Clostridium difficile incidence: a systematic review and meta-analysis | Zendy

Leah M. Feazel | Zendy; Ashish Malhotra | Zendy; Eli N. Perencevich | Zendy; Peter J. Kaboli | Zendy; Daniel J. Diekema | Zendy; Marin L. Schweizer | Zendy

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Effect of antibiotic stewardship programmes on Clostridium difficile incidence: a systematic review and meta-analysis

Author(s) -

Leah M. Feazel,

Ashish Malhotra,

Eli N. Perencevich,

Peter J. Kaboli,

Daniel J. Diekema,

Marin L. Schweizer

Publication year - 2014

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dku046

Subject(s) - clostridium difficile , medicine , meta analysis , antimicrobial stewardship , incidence (geometry) , intensive care medicine , antibiotics , microbiology and biotechnology , biology , antibiotic resistance , physics , optics

Despite vigorous infection control measures, Clostridium difficile continues to cause significant disease burden. Antibiotic stewardship programmes (ASPs) may prevent C. difficile infections by limiting exposure to certain antibiotics. Our objective was to perform a meta-analysis of published studies to assess the effect of ASPs on the risk of C. difficile infection in hospitalized adult patients.

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