Candida glabrata drug:H+ antiporter CgTpo3 (ORF CAGL0I10384g): role in azole drug resistance and polyamine homeostasis | Zendy

Catarina Costa | Zendy; Joaunes | Zendy; Ana Henriques | Zendy; Nuno P. Mira | Zendy; Hironobu Nakayama | Zendy; Hiroji Chibana | Zendy; Miguel C. Teixeira | Zendy

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Candida glabrata drug:H+ antiporter CgTpo3 (ORF CAGL0I10384g): role in azole drug resistance and polyamine homeostasis

Author(s) -

Catarina Costa,

Joaunes,

Ana Henriques,

Nuno P. Mira,

Hironobu Nakayama,

Hiroji Chibana,

Miguel C. Teixeira

Publication year - 2014

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dku044

Subject(s) - candida glabrata , drug resistance , context (archaeology) , antiporter , biology , drug , azole , microbiology and biotechnology , pharmacology , antifungal , biochemistry , paleontology , membrane

The ability of opportunistic pathogenic Candida species to persist and invade specific niches in the human host depends on their resistance to natural growth inhibitors and antifungal therapy. This work describes the role of the Candida glabrata drug:H(+) antiporter CgTpo3 (ORF CAGL0I10384g) in this context.

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