Report of ribosomal RNA methylase gene erm(B) in multidrug-resistant Campylobacter coli
Author(s) -
Shangshang Qin,
Yang Wang,
Q. Zhang,
Michael Zhang,
Fei Deng,
Z. Shen,
Congming Wu,
Shaolin Wang,
Jianzhong Zhang,
Jin-Qiu Shen
Publication year - 2013
Publication title -
journal of antimicrobial chemotherapy
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkt492
Subject(s) - campylobacter , campylobacteriosis , biology , ribosomal rna , microbiology and biotechnology , campylobacter jejuni , multiple drug resistance , drug resistance , gene , genetics , bacteria
Campylobacter is a major foodborne enteric pathogen and macrolides are the drug of choice for the clinical therapy of campylobacteriosis. Macrolide resistance among Campylobacter compromises clinical treatment, is associated with adverse health events and is a significant public health concern. Here, we report the first identification of a horizontally transferrable macrolide resistance mechanism in porcine Campylobacter coli ZC113 that is mediated by a ribosomal RNA methylase, Erm(B).
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