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Epidemiology of penicillin-non-susceptible pneumococci in Iceland, 1995-2010
Author(s) -
Martha Á. Hjálmarsdóttir,
Karl G. Kristinsson
Publication year - 2013
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkt470
Subject(s) - penicillin , medicine , epidemiology , streptococcus pneumoniae , vaccination , pneumococcal infections , antimicrobial , virology , microbiology and biotechnology , antibiotics , biology
The first penicillin-non-susceptible pneumococci (PNSP) were identified in Iceland in 1988. A rapid increase followed, associated with expansion of a single multiresistant clone, Spain(6B)-2, peaking at 19.8% in 1993. After interventions led to reduced antimicrobial use in children, the prevalence of PNSP decreased until 1995. The aim of this study was to follow the evolution of PNSP from 1995 to 2010, the period preceding the introduction of conjugated pneumococcal vaccines into the vaccination programme.

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