An immunomodulatory activity of micafungin in preclinical aspergillosis
Author(s) -
Silvia Moretti,
Silvia Bozza,
Cristina Massi-Benedetti,
Lucia Prezioso,
Elena Rossetti,
Luigina Romani,
Franco Aversa,
Lucia Pitzurra
Publication year - 2013
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkt457
Subject(s) - micafungin , aspergillosis , echinocandins , microbiology and biotechnology , medicine , echinocandin , pharmacology , antifungal , immunology , chemistry , biology , amphotericin b , caspofungin , fluconazole
Micafungin inhibits 1,3-β-D-glucan synthase and interferes with fungal cell wall synthesis. Clinically, micafungin has been shown to be efficacious for the treatment of invasive fungal infections. However, little is known about the immunomodulatory activity of micafungin in these infections.
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