Pharmacokinetic evaluation of the interaction between etravirine and rifabutin or clarithromycin in HIV-negative, healthy volunteers: results from two Phase 1 studies | Zendy

Thomas N. Kakuda | Zendy; Brian Woodfall | Zendy; Tine De Marez | Zendy; Marc Peeters | Zendy; Kati Vandermeulen | Zendy; Fatima Aharchi | Zendy; Richard M. W. Hoetelmans | Zendy

Open Access

Pharmacokinetic evaluation of the interaction between etravirine and rifabutin or clarithromycin in HIV-negative, healthy volunteers: results from two Phase 1 studies

Author(s) -

Thomas N. Kakuda,

Brian Woodfall,

Tine De Marez,

Marc Peeters,

Kati Vandermeulen,

Fatima Aharchi,

Richard M. W. Hoetelmans

Publication year - 2013

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkt421

Subject(s) - rifabutin , etravirine , clarithromycin , pharmacology , tolerability , cefpirome , drug interaction , antibacterial agent , medicine , pharmacokinetics , antibiotics , adverse effect , chemistry , immunology , viral load , human immunodeficiency virus (hiv) , biochemistry , antibiotic resistance , imipenem , antiretroviral therapy , helicobacter pylori

Drug-drug interactions between etravirine and rifabutin or clarithromycin were examined in two separate open-label, randomized, two-period, crossover trials in HIV-negative, healthy volunteers.

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