Persister populations of Mycobacterium tuberculosis in sputum that grow in liquid but not on solid culture media | Zendy

Jasvir Dhillon | Zendy; P. Bernard Fourie | Zendy; D.A. Mitchison | Zendy

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Persister populations of Mycobacterium tuberculosis in sputum that grow in liquid but not on solid culture media

Author(s) -

Jasvir Dhillon,

P. Bernard Fourie,

D.A. Mitchison

Publication year - 2013

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkt357

Subject(s) - sputum , bacilli , microbiology and biotechnology , liquid culture , serial dilution , tuberculosis , mycobacterium tuberculosis , microbiological culture , inoculation , colony forming unit , biology , sputum culture , medicine , bacteria , immunology , pathology , botany , alternative medicine , genetics

Can the characteristics of persisters in cultures of Mycobacterium tuberculosis also be found in bacilli from the sputum of pulmonary tuberculosis patients? The objective of this study was to explore whether the ability of persisters to grow in liquid but not on solid culture media, as in 100 day static cultures, can also be found in bacilli in sputum.

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