Population pharmacokinetics of piperacillin and tazobactam in critically ill patients undergoing continuous renal replacement therapy: application to pharmacokinetic/pharmacodynamic analysis | Zendy

Eduardo AsínPrieto | Zendy; Alicia RodríguezGascón | Zendy; Iñaki F. Trocóniz | Zendy; Amaia Soraluce | Zendy; Javier Maynar | Zendy; José Ángel SánchezIzquierdo | Zendy; Arantxazu Isla | Zendy

Open Access

Population pharmacokinetics of piperacillin and tazobactam in critically ill patients undergoing continuous renal replacement therapy: application to pharmacokinetic/pharmacodynamic analysis

Author(s) -

Eduardo AsínPrieto,

Alicia RodríguezGascón,

Iñaki F. Trocóniz,

Amaia Soraluce,

Javier Maynar,

José Ángel SánchezIzquierdo,

Arantxazu Isla

Publication year - 2013

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkt304

Subject(s) - piperacillin/tazobactam , piperacillin , medicine , pharmacokinetics , renal replacement therapy , renal function , tazobactam , pharmacodynamics , population , dosing , nonmem , antibacterial agent , pharmacology , anesthesia , intensive care medicine , antibiotics , microbiology and biotechnology , biology , genetics , environmental health , bacteria , pseudomonas aeruginosa

To evaluate the pharmacokinetics of piperacillin/tazobactam in critically ill patients undergoing continuous renal replacement therapy (CRRT) and to assess the success of the therapy against susceptible bacteria.

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