Dinuclear polypyridylruthenium(II) complexes: flow cytometry studies of their accumulation in bacteria and the effect on the bacterial membrane | Zendy

F. Li | Zendy; Marshall Feterl | Zendy; Jeffrey Warner | Zendy; F. Richard Keene | Zendy; J. Grant Collins | Zendy

Open Access

Dinuclear polypyridylruthenium(II) complexes: flow cytometry studies of their accumulation in bacteria and the effect on the bacterial membrane

Author(s) -

F. Li,

Marshall Feterl,

Jeffrey Warner,

F. Richard Keene,

J. Grant Collins

Publication year - 2013

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkt279

Subject(s) - ruthenium , membrane , chemistry , ruthenium red , membrane permeability , flow cytometry , membrane potential , bacteria , escherichia coli , biophysics , incubation , biochemistry , biology , microbiology and biotechnology , organic chemistry , genetics , gene , calcium , catalysis

To determine the energy dependency of and the contribution of the membrane potential to the cellular accumulation of the dinuclear complexes [{Ru(phen)2}2{μ-bbn}](4+) (Rubbn) and the mononuclear complexes [Ru(Me4phen)3](2+) and [Ru(phen)2(bb7)](2+) in Staphylococcus aureus and Escherichia coli, and to examine their effect on the bacterial membrane.

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