Declining cephalosporin and fluoroquinolone non-susceptibility among bloodstream Enterobacteriaceae from the UK: links to prescribing change?
Author(s) -
D. M. Livermore,
Russell Hope,
Rosy Reynolds,
Ruth Blackburn,
A. P. Johnson,
N. Woodford
Publication year - 2013
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkt212
Subject(s) - cephalosporin , enterobacteriaceae , microbiology and biotechnology , antibacterial agent , antibiotics , medicine , biology , escherichia coli , genetics , gene
The UK saw major increases in cephalosporin and quinolone resistance amongst Enterobacteriaceae from 2001 to 2006, with cephalosporin resistance largely reflecting dissemination of CTX-M extended-spectrum β-lactamases (ESBLs). We review subsequent trends.
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