Identification of a rare mutation at reverse transcriptase Lys65 (K65E) in HIV-1-infected patients failing on nucleos(t)ide reverse transcriptase inhibitors | Zendy

Slim Fourati | Zendy; Benoît Visseaux | Zendy; Daniele Armenia | Zendy; Laurence MorandJoubert | Zendy; Anna Artese | Zendy; Charlotte Charpentier | Zendy; Peter Van den Eede | Zendy; Giosuè Costa | Zendy; Stefano Alcaro | Zendy; Marc Wirden | Zendy; Carlo Federico Perno | Zendy; Francesca CeccheriniSilberstein | Zendy; Diane Descamps | Zendy; Vincent Cálvez | Zendy; AnneGeneviève Marcelin | Zendy

Open Access

Identification of a rare mutation at reverse transcriptase Lys65 (K65E) in HIV-1-infected patients failing on nucleos(t)ide reverse transcriptase inhibitors

Author(s) -

Slim Fourati,

Benoît Visseaux,

Daniele Armenia,

Laurence MorandJoubert,

Anna Artese,

Charlotte Charpentier,

Peter Van den Eede,

Giosuè Costa,

Stefano Alcaro,

Marc Wirden,

Carlo Federico Perno,

Francesca CeccheriniSilberstein,

Diane Descamps,

Vincent Cálvez,

AnneGeneviève Marcelin

Publication year - 2013

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkt200

Subject(s) - reverse transcriptase , didanosine , stavudine , abacavir , virology , nucleoside reverse transcriptase inhibitor , mutation , resistance mutation , biology , drug resistance , mutant , virus , medicine , lamivudine , zidovudine , polymerase chain reaction , genetics , viral disease , gene , hepatitis b virus

The HIV reverse transcriptase (RT) mutation K65R confers resistance to nucleos(t)ide reverse transcriptase inhibitors (NRTIs). Here, analysing a large database, we report the selection of another rare K65E mutation in patients failing on NRTI-containing regimens.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research