Protective effect of procysteine on Acinetobacter pneumonia in hyperoxic conditions
Author(s) -
Keisuke Saito,
Soichiro Kimura,
Tomoo Saga,
Yoshi Misonoo,
Sadako Yoshizawa,
Yoshikiyo Akasaka,
Toshiharu Ishii,
Kazuyoshi Kuwano,
KYOKO YAMAGUCHI,
Kazuhiro Tateda
Publication year - 2013
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkt192
Subject(s) - hyperoxia , acinetobacter , pneumonia , lung , microbiology and biotechnology , acinetobacter baumannii , medicine , bacterial pneumonia , antibiotics , immunology , biology , bacteria , pseudomonas aeruginosa , genetics
Ventilator-associated pneumonia (VAP) is an important cause of morbidity and mortality in critical care settings. Acinetobacter has become a leading cause of VAP. In particular, the appearance and spread of multidrug-resistant Acinetobacter is of great concern. In this study, we examined the effect of the antioxidant procysteine on Acinetobacter murine pneumonia in hyperoxic conditions in order to simulate VAP.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom