Influence of the MBC/MIC ratio on the antibacterial activity of vancomycin versus linezolid against methicillin-resistant Staphylococcus aureus isolates in a pharmacodynamic model simulating serum and soft tissue interstitial fluid concentrations reported in diabetic patients | Zendy

Natalia González | Zendy; David Sevillano | Zendy; Luís Alou | Zendy; Fabio Cafini | Zendy; María-José Giménez | Zendy; María-Luisa Gómez-Lus | Zendy; J. Prieto | Zendy; Lorenzo Aguilar | Zendy

Open Access

Influence of the MBC/MIC ratio on the antibacterial activity of vancomycin versus linezolid against methicillin-resistant Staphylococcus aureus isolates in a pharmacodynamic model simulating serum and soft tissue interstitial fluid concentrations reported in diabetic patients

Author(s) -

Natalia González,

David Sevillano,

Luís Alou,

Fabio Cafini,

María-José Giménez,

María-Luisa Gómez-Lus,

J. Prieto,

Lorenzo Aguilar

Publication year - 2013

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkt185

Subject(s) - linezolid , staphylococcus aureus , methicillin resistant staphylococcus aureus , pharmacodynamics , vancomycin , microbiology and biotechnology , micrococcaceae , medicine , antibiotics , antibacterial agent , minimum bactericidal concentration , minimum inhibitory concentration , pharmacokinetics , pharmacology , biology , bacteria , genetics

To explore serum and tissue pharmacodynamics of linezolid versus vancomycin against methicillin-resistant Staphylococcus aureus (MRSA) clinical isolates with different MBC/MIC ratios.

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