Community-associated Clostridium difficile infection and antibiotics: a meta-analysis | Zendy

Abhishek Deshpande | Zendy; Vinay Pasupuleti | Zendy; Priyaleela Thota | Zendy; Chaitanya Pant | Zendy; David D.K. Rolston | Zendy; Thomas J. Sferra | Zendy; Adrían V. Hernández | Zendy; Curtis J. Donskey | Zendy

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Community-associated Clostridium difficile infection and antibiotics: a meta-analysis

Author(s) -

Abhishek Deshpande,

Vinay Pasupuleti,

Priyaleela Thota,

Chaitanya Pant,

David D.K. Rolston,

Thomas J. Sferra,

Adrían V. Hernández,

Curtis J. Donskey

Publication year - 2013

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkt129

Subject(s) - clindamycin , medicine , clostridium difficile , antibiotics , risk factor , cephalosporin , trimethoprim , microbiology and biotechnology , biology

Antibiotic exposure is the most important risk factor for Clostridium difficile infection (CDI). Most evaluations of antimicrobial risk factors have been conducted in healthcare settings. The objective of this meta-analysis was to evaluate the association between antibiotic exposure and community-associated CDI (CA-CDI) (i.e. symptom onset in the community with no healthcare facility admission within 12 weeks) and to determine the classes of antibiotics posing the greatest risk.

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