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Effectiveness of penicillin, dicloxacillin and cefuroxime for penicillin-susceptible Staphylococcus aureus bacteraemia: a retrospective, propensity-score-adjusted case–control and cohort analysis
Author(s) -
Jette Nissen,
Robert Skov,
Jenny Dahl Knudsen,
Christian Østergaard,
Henrik Carl Schønheyder,
Niels FrimodtMøller,
Thomas Benfield
Publication year - 2013
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkt108
Subject(s) - medicine , cefuroxime , dicloxacillin , penicillin , propensity score matching , retrospective cohort study , proportional hazards model , surgery , antibiotics , microbiology and biotechnology , biology
Penicillin-susceptible Staphylococcus aureus isolates account for a fifth of cases of S. aureus bacteraemia (SAB) in Denmark, but little is known about treatment outcomes with penicillins or other antimicrobials. Here we compare penicillin, dicloxacillin and cefuroxime as definitive treatments in relation to 30 day mortality.

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