Complexity of resistance mechanisms to imipenem in intensive care unit strains of Pseudomonas aeruginosa | Zendy

PierreEdouard Fournier | Zendy; Charlotte Richardot | Zendy; Emeline Müller | Zendy; Marjorie Robert-Nicoud | Zendy; Catherine Llanes | Zendy; Patrick Plésiat | Zendy; Katy Jeannot | Zendy

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Complexity of resistance mechanisms to imipenem in intensive care unit strains of Pseudomonas aeruginosa

Author(s) -

PierreEdouard Fournier,

Charlotte Richardot,

Emeline Müller,

Marjorie Robert-Nicoud,

Catherine Llanes,

Patrick Plésiat,

Katy Jeannot

Publication year - 2013

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkt098

Subject(s) - pseudomonas aeruginosa , imipenem , porin , efflux , microbiology and biotechnology , biology , mutant , mutation , intensive care , strain (injury) , gene , genetics , bacterial outer membrane , bacteria , medicine , intensive care medicine , escherichia coli , anatomy

Pseudomonas aeruginosa can become resistant to carbapenems by both intrinsic (mutation-driven) and transferable (β-lactamase-based) mechanisms. Knowledge of the prevalence of these various mechanisms is important in intensive care units (ICUs) in order to define optimal prevention and therapeutic strategies.

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