Intraocular penetration of penciclovir after oral administration of famciclovir: a population pharmacokinetic model
Author(s) -
F. Schenkel,
Chantal Csajka,
Edoardo Baglivo,
Mitsuko Kondo-Oestreicher,
Pierre Dayer,
Marianne GexFabry,
Youssef Daali
Publication year - 2013
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkt064
Subject(s) - penciclovir , famciclovir , pharmacokinetics , medicine , oral administration , pharmacology , population , bioequivalence , virology , virus , herpes simplex virus , environmental health
We developed a population model that describes the ocular penetration and pharmacokinetics of penciclovir in human aqueous humour and plasma after oral administration of famciclovir.
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