Chromosome-mediated OXA-48 carbapenemase in highly virulent Escherichia coli
Author(s) -
Racha Beyrouthy,
F. Robin,
Antony Cougnoux,
Guillaume Dalmasso,
Arlette Darfeuille–Michaud,
Hassan Mallat,
Fouad Dabboussi,
Monzer Hamzé,
Richard Bonnet
Publication year - 2013
Publication title -
journal of antimicrobial chemotherapy
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkt051
Subject(s) - virulence , escherichia coli , microbiology and biotechnology , escherichia coli proteins , biology , chromosome , genetics , gene
Bacteria multiresistant to antibiotics are widely supposed to be weakly virulent. However, the virulence traits of carbapenem-resistant Enterobacteriaceae have not been investigated. In this work, we investigated the virulence and resistance mechanism of an extraintestinal pathogenic Escherichia coli (ExPEC) strain (LEB15) that exhibited decreased susceptibility to carbapenems.
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