Clinical implications of antiretroviral drug interactions with warfarin: a case-control study | Zendy

John S. Esterly | Zendy; K. M. Darin | Zendy; Lana Gerzenshtein | Zendy; Farah Waheda Othman | Zendy; Michael Postelnick | Zendy; Kimberly K. Scarsi | Zendy

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Clinical implications of antiretroviral drug interactions with warfarin: a case-control study

Author(s) -

John S. Esterly,

K. M. Darin,

Lana Gerzenshtein,

Farah Waheda Othman,

Michael Postelnick,

Kimberly K. Scarsi

Publication year - 2013

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkt043

Subject(s) - warfarin , medicine , reverse transcriptase inhibitor , ritonavir , gastroenterology , protease inhibitor (pharmacology) , antiretroviral therapy , viral load , human immunodeficiency virus (hiv) , immunology , atrial fibrillation

Warfarin, a frequently prescribed anticoagulant with a narrow therapeutic index, is susceptible to drug-drug interactions with antiretroviral therapy (ART). This study compared the warfarin maintenance dose (WMD) between patients receiving and not receiving ART and evaluated predictors of warfarin dosage among those on ART.

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