Antibacterial activity and mode of action of tert-butylhydroquinone (TBHQ) and its oxidation product, tert-butylbenzoquinone (TBBQ) | Zendy

Nicola Ooi | Zendy; I. Chopra | Zendy; E. Anne Eady | Zendy; Jonathan H. Cove | Zendy; R.A. Bojar | Zendy; Alex J. O’Neill | Zendy

Open Access

Antibacterial activity and mode of action of tert-butylhydroquinone (TBHQ) and its oxidation product, tert-butylbenzoquinone (TBBQ)

Author(s) -

Nicola Ooi,

I. Chopra,

E. Anne Eady,

Jonathan H. Cove,

R.A. Bojar,

Alex J. O’Neill

Publication year - 2013

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkt030

Subject(s) - staphylococcus aureus , chemistry , antibacterial activity , lysis , mode of action , broth microdilution , microbiology and biotechnology , haemolysis , bacterial growth , biochemistry , bacteria , in vitro , biology , minimum inhibitory concentration , genetics , immunology

The antioxidant tert-butylhydroquinone (TBHQ) is a food additive reported to have antibacterial activity, and may therefore have application in the healthcare setting. This study sought to characterize the antibacterial activity and mode of action of TBHQ and its oxidation product, tert-butylbenzoquinone (TBBQ).

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