Frequency of amino acid changes associated with resistance to attachment inhibitor BMS-626529 in R5- and X4-tropic HIV-1 subtype B | Zendy

C. Soulie | Zendy; S. Lambert-Niclot | Zendy; Djeneba Fofana | Zendy; S. Fourati | Zendy; Zaïna Ait-Arkoub | Zendy; Sophie Sayon | Zendy; Anne Simon | Zendy; Christine Katlama | Zendy; Vincent Cálvez | Zendy; AnneGeneviève Marcelin | Zendy

Open Access

Frequency of amino acid changes associated with resistance to attachment inhibitor BMS-626529 in R5- and X4-tropic HIV-1 subtype B

Author(s) -

C. Soulie,

S. Lambert-Niclot,

Djeneba Fofana,

S. Fourati,

Zaïna Ait-Arkoub,

Sophie Sayon,

Anne Simon,

Christine Katlama,

Vincent Cálvez,

AnneGeneviève Marcelin

Publication year - 2013

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkt018

Subject(s) - tropism , human immunodeficiency virus (hiv) , mutation , entry inhibitor , virology , drug resistance , in vivo , virus , biology , lentivirus , in vitro , gene , chemistry , viral replication , microbiology and biotechnology , viral entry , genetics , viral disease

Resistance to attachment inhibitor BMS-626529, which inhibits the binding of HIV to CD4, involves mutations in the HIV-1 gp120 gene. There is a lack of information on the primary resistance of HIV-1 subtype B to attachment inhibitors, so we decided to investigate.

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