Synergy of ultrasound microbubbles and vancomycin against Staphylococcus epidermidis biofilm | Zendy

Ying Dong | Zendy; S. Chen | Zendy; Z. Wang | Zendy; Nianhua Peng | Zendy; Jialin Yu | Zendy

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Synergy of ultrasound microbubbles and vancomycin against Staphylococcus epidermidis biofilm

Author(s) -

Ying Dong,

S. Chen,

Z. Wang,

Nianhua Peng,

Jialin Yu

Publication year - 2012

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dks490

Subject(s) - microbubbles , biofilm , vancomycin , staphylococcus epidermidis , microbiology and biotechnology , ultrasound , staphylococcus aureus , antibiotics , medicine , biomedical engineering , bacteria , biology , radiology , genetics

Device-associated biofilm infections primarily caused by Staphylococcus epidermidis are difficult to treat effectively with conventional antibiotics. The aim of this study was to investigate the anti-biofilm effect of ultrasound-mediated microbubbles combined with vancomycin and to explore underlying mechanisms.

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